Tumor markers are substances found in blood, tissues, or other body fluids that can help identify cancer. They're like warning signs that doctors and laboratory professionals look for during patient testing. Think of them as clues that help healthcare teams detect and monitor cancer. Some common examples include PSA for prostate cancer and CA-125 for ovarian cancer. Healthcare professionals use these markers to screen for cancer, check if treatments are working, or watch for signs that cancer might be returning. While not every cancer produces markers, and some non-cancerous conditions can raise marker levels, they're an important tool in cancer diagnosis and monitoring.
Performed analysis of Tumor Markers in clinical laboratory setting, processing over 200 samples daily
Developed quality control procedures for Tumor Marker testing protocols
Supervised Tumor Markers testing department and trained staff on new testing equipment
Typical job title: "Clinical Laboratory Scientists"
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Q: How would you handle quality control failures in tumor marker testing?
Expected Answer: A senior technologist should explain the importance of following standard protocols, documenting issues, implementing corrective actions, and ensuring proper validation before resuming testing. They should also mention staff training and communication with supervisors.
Q: What experience do you have with laboratory accreditation requirements?
Expected Answer: Should demonstrate knowledge of CAP and CLIA requirements, quality management systems, proficiency testing, and maintaining proper documentation for regulatory compliance.
Q: What are the most common sources of error in tumor marker testing?
Expected Answer: Should discuss sample handling, storage conditions, equipment maintenance, reagent quality, and proper documentation. Should also mention how to prevent these errors.
Q: How do you ensure accurate results when running tumor marker tests?
Expected Answer: Should explain calibration procedures, quality control measures, proper sample handling, and the importance of following standard operating procedures.
Q: What are the basic safety procedures when handling patient samples?
Expected Answer: Should describe proper PPE use, handling of biohazardous materials, waste disposal, and basic laboratory safety protocols.
Q: Explain the basic process of running a tumor marker test.
Expected Answer: Should be able to describe sample preparation, basic testing steps, quality control checks, and result documentation.