Formulation is the process of turning active medical ingredients into usable medicines that can be safely given to patients. Think of it like a recipe - scientists need to combine the main medicine with other ingredients to make it into tablets, capsules, creams, or liquids that are stable, effective, and easy to use. This is a crucial step in drug development, as the way a medicine is formulated affects how well it works in the body. When you see this term in resumes, it usually indicates experience in developing or improving medicine formats in pharmaceutical companies or research labs.
Led development of new Formulation strategies for extending drug shelf life
Managed Formulation development projects for 5 new generic medications
Optimized Formulation process for improved tablet dissolution rates
Successfully completed 15 Formulation and reformulation projects for oral medications
Typical job title: "Formulation Scientists"
Also try searching for:
Q: Can you describe a challenging formulation project you managed and how you overcame the obstacles?
Expected Answer: Look for answers that show leadership in solving complex formulation problems, like dealing with unstable compounds or improving drug delivery methods. They should mention team coordination and decision-making processes.
Q: How do you approach scaling up a formulation from lab to manufacturing?
Expected Answer: Senior candidates should explain how they ensure a smooth transition from small-scale lab testing to full production, including consideration of equipment differences, cost factors, and quality control.
Q: What factors do you consider when choosing excipients for a new formulation?
Expected Answer: They should explain how they select inactive ingredients based on the drug's properties, desired product type (tablet, liquid, etc.), stability requirements, and cost considerations.
Q: How do you ensure the stability of a formulation?
Expected Answer: Candidate should describe stability testing procedures, storage conditions, and how they monitor product quality over time.
Q: What are the basic steps in developing a tablet formulation?
Expected Answer: Should be able to describe the basic process of mixing ingredients, testing for uniformity, and creating the final dosage form in simple terms.
Q: Why is particle size important in formulation?
Expected Answer: Should explain how particle size affects how well the medicine dissolves and works in the body in straightforward terms.