Carry-over refers to the unintended transfer of material from one sample to another during laboratory testing. It's like when a tiny amount from one patient's sample accidentally mixes with the next patient's sample in testing equipment. Understanding carry-over is crucial in medical laboratories because it can affect test results' accuracy. Laboratory professionals need to know how to prevent, detect, and manage carry-over to ensure patient results are reliable. This concept is particularly important in automated testing systems where many samples are processed one after another.
Developed protocols to minimize carry-over in automated chemistry analyzers
Conducted carry-over studies to validate new laboratory equipment
Implemented carry-over detection and prevention strategies in high-volume testing
Typical job title: "Laboratory Technologists"
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Q: How would you implement a laboratory-wide carry-over prevention program?
Expected Answer: Should discuss comprehensive approach including staff training, equipment maintenance, regular testing protocols, documentation procedures, and quality control measures to prevent and detect carry-over.
Q: How do you validate that carry-over is not affecting patient results in a new analyzer?
Expected Answer: Should explain process of running specific test sequences, analyzing high-concentration followed by low-concentration samples, documenting results, and establishing acceptable limits.
Q: What steps do you take when carry-over is detected in routine testing?
Expected Answer: Should describe immediate actions like stopping testing, investigating cause, implementing corrective measures, and documenting incident according to laboratory procedures.
Q: How do you train staff to recognize and prevent carry-over?
Expected Answer: Should discuss training methods, practical demonstrations, quality control procedures, and ongoing monitoring of staff performance.
Q: What is carry-over and why is it important to prevent it?
Expected Answer: Should explain basic concept of sample contamination between tests and its impact on patient results accuracy.
Q: What are some basic steps to prevent carry-over in manual testing?
Expected Answer: Should mention proper sample handling, equipment cleaning, following procedures, and asking for help when unsure.