Analytical Chemistry is a specialized field that focuses on determining what substances are made of and how much of each component is present. In pharmaceutical companies, analytical chemists are essential for ensuring medicine quality, testing new drugs, and making sure products meet safety standards. Think of them as scientific detectives who use various tools and methods to analyze samples and provide detailed information about their composition. This is crucial for drug development, quality control, and regulatory compliance. It's similar to how a food inspector checks ingredients, but at a much more detailed, scientific level.
Led Analytical Chemistry laboratory testing for new drug development projects
Performed Analytical Chemistry and Chemical Analysis for quality control of pharmaceutical products
Supervised Analytical Chemistry team in method development and validation studies
Typical job title: "Analytical Chemists"
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Q: How would you approach method development for a new drug compound?
Expected Answer: A senior analyst should explain the step-by-step process of developing a testing method, including consideration of compound properties, equipment selection, and validation requirements. They should mention regulatory compliance and team coordination.
Q: How do you ensure data integrity in your laboratory?
Expected Answer: Should discuss quality control measures, documentation practices, equipment calibration, and compliance with regulatory requirements like FDA guidelines. Should mention training programs and standard operating procedures.
Q: What quality control measures do you use in sample analysis?
Expected Answer: Should describe basic quality control procedures like running blanks, standards, and duplicates. Should mention documentation requirements and trouble-shooting common problems.
Q: How do you handle out-of-specification results?
Expected Answer: Should explain the investigation process, documentation requirements, and when to involve supervisors. Should mention retesting procedures and root cause analysis.
Q: What safety procedures do you follow in the laboratory?
Expected Answer: Should demonstrate knowledge of basic lab safety: proper protective equipment, handling chemicals safely, waste disposal, and emergency procedures.
Q: How do you maintain laboratory equipment?
Expected Answer: Should describe basic maintenance procedures, cleaning protocols, calibration checks, and documentation requirements. Should know when to call for technical support.