Recruiter's Glossary

Examples: Gene Therapy • Gene Expression • Multiplex PCR

Single Cell Sequencing

Term from Genetic Research industry explained for recruiters

Single Cell Sequencing is a modern laboratory technique that helps scientists understand the unique genetic makeup of individual cells. Think of it as a high-powered microscope that can read the genetic instruction manual (DNA) of one cell at a time, rather than looking at millions of cells together. This is important because even cells that look the same can behave differently. This technique has become very valuable in medical research, especially in studying diseases like cancer, where understanding individual cell behavior is crucial. When you see this term in job descriptions, it usually indicates that the lab or company is doing cutting-edge genetic research.

Examples in Resumes

Performed Single Cell Sequencing analysis on tumor samples for cancer research

Led team projects utilizing Single Cell Sequencing and Single Cell RNA Sequencing techniques

Developed protocols for scRNA-seq and Single Cell Sequencing sample preparation

Typical job title: "Single Cell Sequencing Scientists"

Also try searching for:

Genomics Scientist Single Cell Genomics Researcher Molecular Biologist Bioinformatics Scientist Research Scientist Cell Biology Specialist Genetic Analysis Researcher

Where to Find Single Cell Sequencing Scientists

Professional Organizations

Online Communities

Job Resources

Example Interview Questions

Senior Level Questions

Q: How would you design a single cell sequencing experiment from start to finish?

Expected Answer: A senior scientist should explain the process in simple terms: how they choose samples, prepare them, ensure quality control, and analyze the data. They should mention cost considerations and potential problems they might encounter.

Q: What strategies would you use to manage a large single cell sequencing project?

Expected Answer: Should discuss project planning, team coordination, quality control measures, and how they would handle and store the large amounts of data generated. Should include how they would communicate results to non-technical stakeholders.

Mid Level Questions

Q: What are the main challenges in single cell sequencing sample preparation?

Expected Answer: Should be able to explain common problems like sample contamination, cell preservation, and quality control in simple terms, and how they would solve these issues.

Q: How do you ensure the quality of your single cell sequencing data?

Expected Answer: Should explain basic quality control steps, how they check if an experiment worked well, and what they do if they spot problems with the data.

Junior Level Questions

Q: What is the basic principle of single cell sequencing?

Expected Answer: Should be able to explain in simple terms how the technology works to analyze individual cells, and why this is important for research.

Q: What safety protocols do you follow when handling biological samples?

Expected Answer: Should demonstrate understanding of basic laboratory safety procedures and proper handling of biological materials.