Next Generation Sequencing

Term from Genetic Research industry explained for recruiters

Next Generation Sequencing is a modern way to read and analyze DNA and genetic information quickly and efficiently. Think of it like a very advanced scanner that can read millions of pieces of genetic code at once, instead of doing it one at a time like older methods. This technology helps researchers understand diseases, develop new treatments, and study how genes work. It's sometimes called NGS, high-throughput sequencing, or DNA sequencing. Companies use this technology in medical research, genetic testing labs, and pharmaceutical development.

Examples in Resumes

Processed over 1000 samples using Next Generation Sequencing and NGS technologies

Led team of technicians in Next Generation Sequencing laboratory operations

Optimized Next Generation Sequencing protocols resulting in 40% cost reduction

Typical job title: "NGS Scientists"

Also try searching for:

NGS Technologist Sequencing Specialist Genomics Scientist Bioinformatics Scientist Molecular Technologist Genetic Analysis Specialist Laboratory Technologist

Example Interview Questions

Senior Level Questions

Q: How would you handle a large-scale sequencing project with limited budget?

Expected Answer: Look for answers about optimizing sample batching, choosing cost-effective protocols, implementing quality control measures, and managing resources efficiently while maintaining data quality.

Q: How do you stay current with new developments in sequencing technology?

Expected Answer: Should mention reading scientific journals, attending conferences, participating in professional networks, and experience evaluating new methods and equipment.

Mid Level Questions

Q: What quality control measures do you use in NGS?

Expected Answer: Should discuss sample quality checking, library preparation standards, and how to identify and handle poor quality results.

Q: Explain how you troubleshoot failed sequencing runs.

Expected Answer: Should describe systematic approach to identifying problems, from sample preparation to machine operation, and steps to prevent similar issues.

Junior Level Questions

Q: What is the basic workflow of an NGS experiment?

Expected Answer: Should be able to describe main steps: sample preparation, library creation, sequencing, and basic data analysis.

Q: What safety procedures are important when handling samples?

Expected Answer: Should demonstrate knowledge of basic lab safety, proper sample handling, contamination prevention, and waste disposal.

Experience Level Indicators

Junior (0-2 years)

  • Basic lab techniques and safety procedures
  • Sample preparation and handling
  • Following established protocols
  • Basic equipment operation

Mid (2-5 years)

  • Independent experiment planning
  • Troubleshooting technical issues
  • Data quality assessment
  • Protocol optimization

Senior (5+ years)

  • Project planning and management
  • Advanced protocol development
  • Team leadership and training
  • Budget management

Red Flags to Watch For

  • No hands-on laboratory experience
  • Lack of attention to detail in sample handling
  • Poor understanding of contamination risks
  • No experience with quality control procedures
  • Unable to explain basic sequencing concepts