microRNA
microRNA (also known as miRNA) is a tiny but important piece of genetic material that helps control how genes work in living things. Think of it like a tiny switch that can turn genes on or off. Scientists study these molecules because they play key roles in health and disease. When candidates mention microRNA experience, they're typically talking about working with these genetic regulators in research labs, often using special equipment and techniques to study how they affect different diseases or biological processes. This is similar to working with other genetic materials like DNA and RNA, but focuses specifically on these smaller regulatory molecules.
Examples in Resumes
Identified novel microRNA markers for early cancer detection
Developed and optimized miRNA extraction protocols
Led research team studying microRNA involvement in stem cell development
Typical job title: "microRNA Research Scientists"
Also try searching for:
Where to Find microRNA Research Scientists
Scientific Communities
Job Boards
Professional Networks
Example Interview Questions
Senior Level Questions
Q: How would you design a research project to identify new microRNAs involved in a specific disease?
Expected Answer: A senior researcher should discuss project planning steps including experimental design, controls, methodology selection, and how to validate findings. They should mention both wet lab and computational approaches.
Q: How do you stay current with new developments in microRNA research?
Expected Answer: Should discuss reading scientific journals, attending conferences, participating in collaborations, and understanding how to evaluate new research techniques and findings.
Mid Level Questions
Q: What methods do you use to validate microRNA targets?
Expected Answer: Should be able to explain common laboratory techniques used to confirm microRNA interactions, such as using reporter genes or measuring protein levels, in simple terms.
Q: Describe your experience with microRNA data analysis.
Expected Answer: Should discuss experience with analyzing experimental results, using basic bioinformatics tools, and interpreting data to draw conclusions.
Junior Level Questions
Q: What are the basic steps in isolating microRNA from a sample?
Expected Answer: Should be able to describe the general process of extracting microRNA from biological samples and basic lab safety procedures.
Q: What is the difference between microRNA and other types of RNA?
Expected Answer: Should explain in simple terms that microRNAs are smaller molecules that help control gene activity, compared to other types of RNA that have different functions.
Experience Level Indicators
Junior (0-2 years)
- Basic lab techniques and safety
- Sample preparation and handling
- Following established protocols
- Data recording and documentation
Mid (2-5 years)
- Independent experiment design
- Data analysis and interpretation
- Troubleshooting technical problems
- Writing research reports
Senior (5+ years)
- Project leadership and planning
- Grant writing and funding acquisition
- Training and supervising junior staff
- Publishing research findings
Red Flags to Watch For
- No hands-on laboratory experience
- Unfamiliarity with basic molecular biology techniques
- Poor documentation practices
- Lack of understanding of experimental controls
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