Limit of Quantification

Term from Laboratory Testing industry explained for recruiters

The Limit of Quantification (LOQ) is a basic quality measure used in laboratory testing that shows how well a lab can measure very small amounts of substances. Think of it like a microscope's ability to see tiny details - the better it is, the smaller things it can measure accurately. When someone lists LOQ experience on their resume, it means they know how to determine and work within these measurement limits, which is important for accurate lab results. You might also see it called "quantitation limit" or "reporting limit" in job descriptions.

Examples in Resumes

Improved Limit of Quantification methods resulting in 30% more accurate measurements

Validated testing procedures by establishing LOQ for new analytical methods

Trained junior analysts in determining Limit of Quantification for various test methods

Typical job title: "Laboratory Analysts"

Also try searching for:

Analytical Chemist Quality Control Analyst Laboratory Technician Method Development Scientist Validation Specialist Quality Assurance Analyst

Where to Find Laboratory Analysts

Example Interview Questions

Senior Level Questions

Q: How would you establish LOQ for a new testing method?

Expected Answer: A senior analyst should explain the process in simple terms: running multiple tests at different concentrations, checking accuracy and precision, and setting reliable measurement limits that meet quality standards.

Q: How do you train others in understanding and working with LOQ?

Expected Answer: Should discuss making complex concepts simple for new staff, creating clear procedures, and ensuring consistent quality across the lab team.

Mid Level Questions

Q: What factors can affect LOQ in daily testing?

Expected Answer: Should mention practical factors like sample preparation, equipment condition, and environmental conditions that can impact measurement accuracy.

Q: How do you document and report LOQ in your work?

Expected Answer: Should explain how they record and communicate measurement limits in reports and documentation, ensuring clarity for clients and regulators.

Junior Level Questions

Q: What is LOQ and why is it important?

Expected Answer: Should be able to explain that LOQ is the smallest amount that can be reliably measured and why this matters for accurate lab results.

Q: How do you know if a measurement is below LOQ?

Expected Answer: Should demonstrate basic understanding of measurement limits and standard procedures for handling results below detection limits.

Experience Level Indicators

Junior (0-2 years)

  • Basic understanding of measurement limits
  • Following established LOQ procedures
  • Sample preparation
  • Basic data recording and documentation

Mid (2-5 years)

  • Method validation
  • Quality control procedures
  • Troubleshooting analytical methods
  • Data analysis and reporting

Senior (5+ years)

  • Method development
  • Training and supervision
  • Quality system management
  • Regulatory compliance

Red Flags to Watch For

  • No understanding of basic measurement principles
  • Unable to explain quality control procedures
  • Lack of documentation experience
  • No knowledge of laboratory safety practices