A bioreactor is a specialized container or system used to grow living cells, microorganisms, or tissues in a controlled environment. Think of it like a high-tech growing chamber where scientists can carefully manage conditions like temperature, oxygen, and nutrients to produce various biological products. Companies use bioreactors to make things like medicines, vaccines, food additives, and sustainable materials. When you see this term in a resume, it usually indicates that the candidate has experience with bioprocessing equipment and understands how to maintain sterile conditions and monitor biological production processes.
Operated and maintained 500L Bioreactor systems for vaccine production
Optimized growth conditions in Bioreactor resulting in 30% increased product yield
Managed multiple Bioreactors for cell culture development and protein production
Typical job title: "Bioprocess Engineers"
Also try searching for:
Q: How would you troubleshoot a contaminated bioreactor batch?
Expected Answer: A senior candidate should explain a systematic approach: checking sterility controls, reviewing batch records, analyzing contamination type, implementing corrective actions, and developing preventive measures for future batches. They should also mention documentation and team coordination.
Q: How do you scale up a process from laboratory to production scale?
Expected Answer: Should discuss risk assessment, parameter adjustments, validation steps, and how to maintain product quality during scale-up. Should mention experience with different sizes of equipment and understanding of regulatory requirements.
Q: What parameters do you monitor in a bioreactor and why?
Expected Answer: Should list key parameters like temperature, pH, oxygen levels, and nutrient concentrations, explaining why each is important for cell growth and product quality.
Q: Describe your experience with different types of bioreactors.
Expected Answer: Should be able to compare different bioreactor designs (stirred tank, airlift, etc.) and explain their appropriate uses based on product type and scale.
Q: What are the basic components of a bioreactor?
Expected Answer: Should identify main parts like vessel, sensors, control systems, and explain basic functions like temperature control and mixing.
Q: How do you maintain sterility in a bioreactor?
Expected Answer: Should explain basic cleaning procedures, sterilization methods, and importance of aseptic technique in bioreactor operations.